The ongoing war between Iran and a US-Israeli coalition has resulted in the deaths of numerous high-ranking Iranian officials, including Supreme Leader Ayatollah Ali Khamenei, who was killed on February 28, 2026, in an initial strike on Tehran. Other significant casualties include Security Chief Ali Larijani, Revolutionary Guards chief Mohammad Pakpour, and Guards naval chief Alireza Tangsiri, who died of wounds sustained on March 28, 2026. Despite these losses, the Islamic Republic has demonstrated resilience by rapidly replacing fallen leaders and continuing its war efforts. US President Donald Trump has declared that the conflict has achieved "regime change," though Iran's ability to maintain its leadership structure and military operations suggests otherwise.