President Donald Trump's recent threat to destroy "a whole civilisation" in Iran has sparked widespread condemnation and renewed calls for invoking the 25th Amendment, which allows for the removal of a president deemed unfit to serve. Despite bipartisan criticism, including from former allies like Marjorie Taylor Greene and Tucker Carlson, the mechanism is considered politically unfeasible due to the requirement for the Vice President and a majority of the cabinet to agree, followed by a two-thirds congressional majority to override a presidential challenge. Experts like Mario Del Pero and Denis Lacorne view the 25th Amendment as largely inoperable in such circumstances, citing Trump's cabinet of loyalists and the superficial nature of dissent within the MAGA base. While Trump later announced a two-week ceasefire, the political storm persists, with courts and potential Democratic gains in the 2026 midterms seen as more likely checks on his power than constitutional amendments.