The tragic case of two-year-old Domenico in Naples, Italy, has concluded with his death following a failed heart transplant. Domenico, born with a severe heart defect, had finally received a donor heart shortly before Christmas, but the organ was severely damaged during transport due to improper cooling with dry ice instead of standard ice. Despite the irreparable damage, doctors proceeded with the transplant, keeping Domenico alive on an ECMO machine. Weeks later, with his condition deteriorating and other organs failing, a decision was made that further surgery was futile. His mother, Patrizia Mercolino, expressed her devastation and intent to establish a foundation in his name. The incident has sparked widespread outrage in Italy, leading to investigations against six medical professionals and internal reviews by the hospital.